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VC FundPuts its own capital into companiesActive · deal in last 18 monthsLAST VERIFIED Oct 2026 · 15 SOURCES

CRB Health Tech

Also known as CRB Health Tech, S.G.E.I.C., S.A., CRB Inverbio, CRB Inverbío, Cross Road Biotech

Madrid/Barcelona life-science and digital-health VC manager founded 2008 (formerly CRB Inverbio); its third fund, CRB Digital Health III, closed at €50M in 2026.

HEADQUARTERS
Madrid, Spain
FOUNDED
2008
AUM
—
OUTSIDE CAPITAL
Yes
TEAM LISTED
8 people

Focus

STAGES
SeedSeries A
ASSET MIX
Venture capital
GEOGRAPHY
SpainEurope

Overview

CRB Health Tech, S.G.E.I.C., S.A. (formerly CRB Inverbio) is a CNMV-registered manager (no. 87, October 2010) founded in 2008, with offices in Madrid and Barcelona. Its first two funds invested in biotech, diagnostics and medical devices; CRB Bio II exited Health in Code in February 2026. Its third fund, CRB Digital Health III, closed at €50M in May 2026 against a €30M target, backed by Sanitas, Roca Group, CBNK, Cantabria Labs and other corporates, family offices, SETT, CDTI, ICF and Barcelona City Council.

Investment thesis

Digital health companies past clinical or regulatory validation: digital diagnostics and AI applied to diagnosis, digital therapeutics and virtual care, health-data integration and hospital digitalisation. Tickets €500K–€1.5M, up to €4–5M per company, at seed and Series A in Spain and Europe.

PORTFOLIO (12)

  • Health in CodeNOTABLE
    Biotech & Life Sciences · since 2013 · Exited (2026, Alantra continuation vehicle)
  • Artificial Intelligence · since 2026
  • Eholo
    HealthTech · since 2026
  • HealthTech · since 2026
  • Circle Health
    HealthTech
  • Trak
    HealthTech
  • Zoundream
    HealthTech
  • Thryve
    HealthTech
  • Livo
    HealthTech
  • AMADIX
    Biotech & Life Sciences
  • Oncovision
    HealthTech
  • NUUBO
    HealthTech

People

  • Enrique Castellón
    Partner (founding partner; chairman per press) · source
  • Ángel Santos
    Partner · source
  • Joaquín Velasco
    Partner · source
  • Manuel Castellón
    Partner · source
  • Alejo Costa Ribalta
    General Partner · source
  • Ignasi Heras Vila
    General Partner · source
  • Tim Juergens
    Partner · source
  • María Jaraiz
    Partner · source

Links

Frequently asked questions

CRB Health Tech is a VC fund based in Madrid, Spain, founded in 2008.

Yes. CRB Health Tech invests its own capital in private companies.

CRB Health Tech invests at Seed and Series A stages in HealthTech, Biotech & Life Sciences and Artificial Intelligence.

CRB Health Tech's stated ticket size is €500K–€1.5M.

Key people at CRB Health Tech include Enrique Castellón (Partner (founding partner; chairman per press)), Ángel Santos (Partner), Joaquín Velasco (Partner) and Manuel Castellón (Partner).

CRB Health Tech's investments include Health in Code, Waiv (formerly Owkin Dx), Eholo, AssistMe, Circle Health, Trak, Zoundream and Thryve, among others.

The most recent publicly reported investment by CRB Health Tech is Eholo, announced in Aug 2026.

Yes. CRB Health Tech manages capital from outside investors.